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SSRIs work by inhibiting the reuptake of serotonin at specific receptors, thereby increasing serotonin activity and concentration (1)

In addition, miR-204-3p in macrophages was also demonstrated to be a protective factor in MASLD progression by ameliorating macrophage inflammation and coordinating macrophage actions on hepatocytes and HSCs to alleviate steatohepatitis and fibrosis [120]

Wegovy: Once in use, it can be kept at room temperature (below 30C) for up to 28 days Liraglutide: Once in use, it can be kept at room temperature (below 30C) for up to 30 days Neither medication should be frozen

In head-to-head clinical trials, tirzepatide has outperformed semaglutide