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deficiency limits this, causing unmet NADPH demand and hemolysis. Older erythrocytes hemolyze first due to lower G6PD activity. Reticulocytosis follows initial hemolysis, conferring resistance. G6PD Deficiency Role G6PD deficiency impairs NADPH production, the sole RBC source, making cells vulnerable to primaquines oxidative stress
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This table outlines its major functions and why each matters: How Is Glutathione Administered Intravenously
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