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Stegeman I, Eikelboom RH, Smit AL, et al

Unfortunately, you also need to worry about stress inside your body, which can lead to damage on a cellular level

It cautions against the oversimplified classification of targets as purely pro- or anti-ferroptotic and emphasizes the need for cell-type-specific mechanistic studies

Because superoxide cannot cross the membrane of mitochondria, it reacts with water to form hydrogen peroxide, which is very susceptible to spontaneously passing out of the membrane [27]