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Similarly, among those who discontinued an SGLT2 inhibitor, the cumulative incidence of reinitiating treatment was 40.4% (95% CI 39.9, 40.8) at 1 year and 55.7% (95% CI 55.2, 56.2) at 3 years when using a grace period of 90 days (Fig

The route of delivery suggests that the peptides will be able to interact with the GLP-1 receptors on the vagal afferents of the intestine, as is the case for native GLP-1 in healthy individuals

McGeer EG, McGeer PL