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In contrast, babies delivered by cesarean section have poorer gut microbiota, dominated by Staphylococcus, Streptococcus , and Clostridium , and a significant deficiency of Bifidobacteria (155)
Reference intervals were established for children for four age groups from birth to 13y
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Phase 2 dose-finding trial (Lancet 2021) showed clear dose-response from 0.3 mg up to 4.5 mg/week, but 2.4 mg is the dose Novo Nordisk advanced into Phase 3 and is the most commonly self-reported community ceiling
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