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We also explored the root causes of failures and explained actionable remediation strategies

In the present study, elevated PGA levels were observed among 89% of symptomatic TTR-V30M patients and in 63% of asymptomatic carriers relative to the median of healthy controls (Table 1)

Severe hyperhomocysteinemia in patients is able to develop neurological and cardiovascular disorders as well as premature death owing to complications [106]

The official product-specific event that appears prominently is the 2019 recall of lot W20308 for potential lack of sterility assurance, which was a manufacturing recall rather than a counterfeit alert