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Allergy 63(2):181188
The enrolled patients suffered from peripheral mono- and polyneuropathies of various origins including entrapment, traumatic, toxic/alcoholic, diabetic, metabolic, idiopathic, vascular or infective aetiology
Consequently, the proportion of lean body mass relative to total body weight increased
The absence of leg cramps from official labeling does not definitively rule out a connection, as post-marketing experience sometimes reveals adverse effects not detected in pre-approval trials due to sample size limitations, duration of follow-up, or patient population differences
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