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L-cells, the specialized cells lining our digestive tract that produce appetite-suppressing hormones like GLP-1, have receptors on their surface that respond to carbohydrates, proteins, and fatsas well as detect bitter compounds, like the quinine in tonic water that Ive talked about before, as well as pungent molecules, as I detailed in my video on spices
Previous studies that explored the effects of larger peptide GLP-1s such as semaglutide in the brain have found that they suppress hunger-driven eating by engaging networks in the hypothalamus and hindbrain
Whether you are looking at branded medications or compounded alternatives, the goal remains the same: finding a safe, effective, and sustainable way to manage your metabolic health
So while GLP-1s can have a negative effect on one inflammatory marker (white blood cells, listed above), theyre likely to have a positive effect on this one
