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These pathways converge to influence immune cell differentiation, trafficking, and effector function, ultimately conditioning the tumor immune microenvironment (Fig
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10.1016/j.gendis.2022.11.022 Summary Keywords gemcitabine, resistance mechanism, tumor microenvironment, combination therapy, precision medicine Citation Zhang X, Qi B and Chen J (2025) Clinical application and drug resistance mechanism of gemcitabine
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