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This is a process where unstable molecules called free radicals cause damage to cellular structures
In an oxidative ER environment, activated ERO1 generates disulfide bonds by consuming O 2 in the presence of flavin cofactors, which are then passed to the protein for folding via PDI (Wang et al., 2014)
Scientific sources Raun K, Hansen BS, Johansen NL, et al
J Am Soc Nephrol 25(8):18251833 He Y, Wang S, Li Y, Deng J, Huang L (2023) Effects of atorvastatin in suppressing pulmonary vascular remodeling in rats with chronic obstructive pulmonary disease
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