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Rybelsus isnt approved for weight loss, but patients in clinical trials lost an average of 5 pounds over 6 months on the lowest dose
By comparison, this revised peak estimate is more than double the $79 billion in total sales recorded in 2025
In the UK, GLP-1 receptor agonists are primarily prescribed for two main indications : type 2 diabetes mellitus and weight management in adults with obesity or overweight with weight-related comorbidities
Meanwhile, plus-size shoppers worry about the decline in inclusive sizing and skinny culture reasserting its dominance
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