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Studies have examined how these metabolic changes affect various cellular processes including energy metabolism and gene expression
Evidence is insufficient for weight loss (failed Phase 2b trial) and preliminary for osteoarthritis (small open-label studies without adequate controls)
Patients were to be randomized to 1200 mg, 450 mg, or placebo, administered intravenously daily for 3 days followed by weekly for 4 weeks
For instance, in rodent models of colitis, administration of BPC-157 has been linked to a significant reduction in inflammatory markers and macroscopic signs of damage
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