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Large-scale evidence offers cautious reassurance after inadvertent GLP-1 exposure in pregnancy, but unresolved risks and low-certainty data mean routine use cannot yet be considered safe

Clinical Data: Women using Semaglutide reported losing an average of 1015% of their body weight, compared to those on metformin, who typically see only modest weight-related benefits

For example in familial hypercholesterolemia the level of LDL-Lp-PLA 2 activity increases in parallel with the severity of the hypercholesterolemia

Consistent once-weekly dosing is important, and injectable semaglutide can be administered irrespective of meals