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Risk assessment should be individualized
Given semaglutide's 7-day half-life (Kapitza et al., J Clin Pharmacol, 2015), injecting 0.25 mg every 10 to 14 days maintains a lower average steady-state concentration than weekly dosing
Preclinical BPC-157 tendon and ligament rat studies used 714 day dosing windows [6]
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