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Yang J, Chen C, McLaughlin T, Wang Y, Le YZ, Wang JJ, et al
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Many patients notice appetite suppression and weight loss within the first few weeks, with significant progress over several months
Key Difference: Tirzepatide (Mounjaro/Zepbound): Dual GIP/GLP-1 agonist Semaglutide (Wegovy/Ozempic): GLP-1 agonist only Effectiveness Difference: Tirzepatide: 15-22% average body weight loss Semaglutide: 10-15% average body weight loss Semaglutide is less potent but still highly effective and significantly more affordable than brand-name tirzepatide
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