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In this Review, we summarize current preclinical and clinical evidence, showing that the riskbenefit profile of GLP1RAs remains favourable in individuals with T2DM and obesity, although caution is warranted in those with a low cardiometabolic risk, for whom the potential risks of cancer might outweigh any expected benefits
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For people with elevated BMIs, it may be worth doing a trial of lifestyle interventions, such as diet and exercise, before adding a medication to the treatment, says Dr
It may also aid in enhancing cognitive function and reducing symptoms of neurological disorders like Parkinsons disease
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