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Its effect is specific to adipose tissue metabolism
Those with diseases that affect the gut, such as Crohns disease or celiac disease, are also at risk ( Summary Those at greatest risk of vitamin B12 deficiency are vegans and vegetarians, who get little to no B12 from the diet
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A 2013 study linked low vitamin B12 and folate levels with an increased risk of age-related macular degeneration ( Although the reduction in risk cant be attributed to vitamin B12 only, it does suggest that getting enough may be important
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