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doi: 10.1111/dom.12808 67 WangC.LiC.PengH.YeZ.ZhangJ.LiuX.et al
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Nausea occurs in 1520% of users at doses above 0.12mg/kg and is caused by melanocortin receptor activation in the brainstem's area postrema (the vomiting center)
The gradual onset of effects, while sometimes frustrating, reflects the medication's design to minimize side effects while maximizing sustainable metabolic benefits over time
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