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High resolution mass spectrometry of GSH (50 mM) in the presence of Ru(II)-OH (2 mM) were directly conducted after preparation and after incubation for 12 h

The mechanism appears to involve increased serotonin synthesis in substantia nigra (both compacta and reticulata), a regional pattern unlike any existing antidepressant drug, plus potential dopaminergic contributions given the nigrostriatal location

Taranta A, Bellomo F, Petrini S, Polishchuk E, De Leo E, Rega LR, Pastore A, Polishchuk R, De Matteis MA, Emma F (2017) Cystinosin-LKG rescues cystine accumulation and decreases apoptosis rate in cystinotic proximal tubular epithelial cells

The easiest approach is using peptides that don't require daily dosing