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106-OR: A First-in-Human Single Ascending Dose Study of Oxyntomodulin Analog LY3305677 in Healthy Subjects
Packer M, Zile MR, Kramer CM, Baum SJ, Litwin SE, Menon V et al
It has recently been shown that GLP-1R neurons in the dorsomedial hypothalamic nucleus regulate pancreatic activity by affecting the dorsal motor nucleus of the vagus, specifically lowering blood glucose levels by increasing insulin release (Xie et al., 2022)
doi: 10.1210/clinem/dgz175 4 NauckMAHeimesaatMMOrskovCHolstJJEbertRCreutzfeldtW
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