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Preclinical studies showed that weight loss was driven by both reduced caloric intake and increased metabolic expenditure
It has been proposed that many pregnancy related disorders including recurrent embryo implantation failure, miscarriage, preterm labor and preeclampsia are related to abnormal induction of tolerance
Given that M-cells have well-accepted BT capability and overlie intestinal lymphoid aggregates, M-cell mediated BT is one plausible mechanistic explanation [16, 17]
M., Haber, M
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