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Similar content being viewed by others 1 Introduction GLP-1 is an endogenous incretin hormone produced by intestinal L-cells that modulates postprandial glucose levels via glucose-dependent insulin production, offering intrinsic protection against hypoglycemia (Zander et al
PIONEER 3 PIONEER 3 compared the efficacy and safety of the addition of oral semaglutide or the DPP-4 inhibitor sitagliptin as add-on therapy in patients with T2DM receiving metformin with or without a sulfonylurea
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