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Activation of aerobic glycolysis-related bypass pathways Increased glycolysis simultaneously activates multiple self-associated bypass pathways, among which the PPP provides the raw material for purine and pyrimidine nucleotide synthesis and maintains redox homeostasis for cancer cell growth, which largely depends on the activity of glucose-6-phosphate dehydrogenase (G6PD), as it catalyzes the first step of the glucose-6-phosphate shift to the PPP [46]

C ssav = AUC 0t /, is the interval of administration;C ssmin =(C -48h + C -24h + C 0h )/3

An effective approach combines the right fiber type with proper hydration and timing

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