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NAFLD induces insulin resistance and exacerbates systemic chronic inflammation and oxidative stress, which leads to organ dysfunction in extra-hepatic tissues
3 Results The initial search yielded 5221 potentially relevant references of which 40 records were retrieved for full-text review (Fig
doi: 10.1016/S2352-3018(16)30215-6 144 TwiggHL 3rdKnoxKSZhouJCrothersKANelsonDETohEet al
Dosing Titration: Trials typically begin with a low "induction" dose (e.g., 0.25mg) to minimize gastrointestinal distress, gradually increasing the dosage over several months
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