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So if something goes wrong and the GSSG accumulates, it inhibits an enzyme that relies on the correct oxidation of the ER environment to operate a protein quality control system. Moreover, they discovered, when misfolded proteins dont pass quality control, they wont get exported, so they too pile up in the ER
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These include ozonation, ionizing radiation, cold plasma, UV radiation, biotic elicitors, and edible films enriched with natural antimicrobial substances or nano-metals (Lo Piccolo et al., 2020)
This slowing down links to getting older and certain health hiccups that come with it
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