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Key Findings: Asian participants: 21.3% mean weight loss with CagriSema (similar to overall population) Safety profile consistent across ethnicities GI tolerability similar but potentially lower discontinuation rates in Asian populations Clinical Significance: Supports global applicability of cagrilintide-based therapies across diverse populations

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Unlike BPC-157, TB-500 injection location matters less because it distributes systemically

2.12 Colony-formation analysis Cells (1000 per well) were plated in culture plates for 1 weeks at 37C in a humidified environment with 5% CO 2 and stained with crystal violet staining solution(1%) for 10~20 min