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Cell (2012) 150(2):25163
After kids, its a medicine my body needed, she says
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To this regard, GSH may also have direct anti-SARS-CoV-2 potential: indeed a computational study indicates that the binding of spike protein to ACE2 is maximal when ACE2-sulfur groups are in the form of disulfides and impaired when fully reduced to thiols: hence a prooxidant environment with low levels of GSH would favor viruses cellular entry (Hati and Bhattacharyya, 2020)
The three antioxidants were successful in decreasing the gene expression of ACC and FAS, with ASTX being the molecule with the greatest inhibitory capacity (55)
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