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GLP-1 medications, including Ozempic, Wegovy, and Zepbound, were originally developed to help regulate blood sugar and are now commonly prescribed for a range of health concerns including diabetes and what many in the healthcare field refer to as weight management

Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4

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Stressed and injured NASH hepatocytes express and secrete a second Hedgehog ligand, Sonic Hedgehog (SHH), which is positively correlated with hepatocyte ballooning, steatosis, pericellular fibrosis, and fibrosis stage in liver samples from NASH patients (206, 207)