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Protease is a vital enzyme that facilitates the breakdown of proteins into smaller peptides and amino acids during digestion

Regarding migraine headache, administration of pyridoxine has decreased headache attack severity and duration in comparison with placebo, with no effect on frequency (72)

Effect of Increased Lactate Dehydrogenase A Activity and Aerobic Glycolysis on the Proinflammatory Profile of Autoimmune CD8+ T Cells in Rheumatoid Arthritis

For PsA, according to the last ACR guidelines, anti-TNF- cycling is preferred over anti-IL-17 and anti-IL-12/23 inhibitor use after anti-TNF- failure, except of the case of severe psoriasis or primary anti-TNF- non-response [131]