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doi: 10.1055/s-0042-109065 Summary Keywords diabetes mellitus type 2, cardiovascular disease, cardiovascular risk, diabetic kidney disease, sodium-glucose cotransporter-2 inhibitor, glucagon-like peptide-1 receptor agonist, aldosterone, renin Citation Puglisi S, Rossini A, Poli R, Dughera F, Pia A, Terzolo M and Reimondo G (2021) Effects of SGLT2 Inhibitors and GLP-1 Receptor Agonists on Renin-Angiotensin-Aldosterone System
Cardiovascular and Endothelial Benefits GLP-1 RAs have demonstrated robust cardiovascular protection in multiple large-scale trials, including LEADER, REWIND, and SUSTAIN-6, showing reduced rates of major adverse cardiac events independent of weight loss
This medication can increase the risk of infections, so your doctor will likely screen you for tuberculosis (TB) and other underlying infections
Mazdutide, was designed by Innovent (Originally IBI362) to mimic OXM but had chemical modifications to extend its half-life , to around 7.5-9.8 days [30]
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