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This proton transport results in the establishment of an energy gradient (proton motive force, PMF) which is used to power the synthesis of ATP from ADP and inorganic phosphate (P i ) as the protons flow down the gradient back into the matrix through the ATP synthase complex

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developed a 122 nm self-assembled nanoparticle (TMNPs) that utilizes a serum albumin corona to engage the megalin receptor, facilitating selective uptake by proximal tubular epithelial cells