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(Source: iPharma Pharmacy, 2026) A 2026 systematic review and meta-analysis (Prospero CRD42024535096) searched Cochrane Library, EMBASE, and Medline through September 2024, identifying 9,654 studies and including 11 randomized controlled trials comparing GLP-1 receptor agonists against no treatment, placebo, lifestyle intervention, oral contraceptives, anti-androgens, or metformin in PCOS patients
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GSH deficiency or a decrease in the GSH/glu-tathione disulfide ratio manifests itself largely through an increased susceptibility to oxidative stress, and the resulting damage is thought to be involved in diseases, such as cancer, Parkinson's disease, and Alzheimer's disease
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