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By using a large multi-institutional database, the researchers were able to evaluate long-term outcomes in this patient population

Change history 13 May 2024 A Correction to this paper has been published: Abbreviations ASL-MRI: Arterial spin labelling MRI BOLD-MRI: Blood oxygen level-dependent MRI CKD: Chronic kidney disease DKD: Diabetic kidney disease GLP-1: Glucagon-like peptide-1 GLP-1ra: Glucagon-like peptide-1 receptor agonist P-EPO: Plasma erythropoietin R2*: Apparent relaxation rate R2 SGLT1/2: Sodiumglucose cotransporter 1/2 SGLT2i: Sodiumglucose cotransporter 2 inhibitor TLCO: 12-layer concentric objects UACR: Urine albumin/creatinine ratio References Zheng Y, Ley SH, Hu FB (2018) Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

One drug may be better tolerated by some patients than another

Yet, results from another two-year, randomized controlled trial the T reatment O f N onalcoholic fatty liver disease I n C hildren (TONIC) in 173 children (ages, 8-17 years) with MAFLD failed to observe any significant reduction in blood concentrations of alanine and aspartate aminotransferases either with supplemental vitamin E (536 mg/day of RRR --tocopherol) or with metformin (an anti-diabetic drug