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RGN-352 was shown to be safe and well-tolerated with no serious drug-related adverse events reported (PMID: 20536472) Phase 2 AMI trial (incomplete): RegeneRx designed a Phase 2 proof-of-concept trial (NCT01311518) to evaluate RGN-352 in approximately 75 patients with acute ST-segment elevation myocardial infarction (heart attack)

Decision framework for compromised peptides Definitely discard if: visible precipitation, significant color change, unusual odor, reconstituted solution left at room temperature more than 4 hours, or lyophilized peptide at warm temperature for more than 2 weeks

To facilitate quantification of GSH, additional spectra were collected from the same volume of interest (Figure 4) using a short-echo PRESS sequence with vapor water suppression (repetition time=2,000 ms, echo time=36 ms

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