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Research has demonstrated involvement of the NO system, growth factor modulation (including VEGF, EGF), and FAK-paxillin signaling pathways

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While lyophilised (freeze-dried) BPC-157 is considerably more robust than reconstituted liquid, it is still susceptible to rapid thermal degradation if exposed to excessive heat for prolonged periods

This synthetic 11-amino-acid peptide, also known as cibinetide, has completed multiple human clinical trials specifically targeting neuropathy, with results that have attracted FDA Fast Track designation and orphan drug status