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A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib
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Of significance to diabetes is that ER stress-induced inflammation activates the kinases JNK (JUN N-terminal kinase) and IKK (inhibitor of nuclear factor-kappa B kinase subunit beta) that phosphorylate insulin receptor substrates (e.g
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