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Summary Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as a new antidiabetic drug class with multiple metabolic effects
Under hypoxic or hyperglycemic conditions, the accumulation of HIF1 markedly drives renal tubular cell ferroptosischaracterized by HO1/TFRC upregulation, iron overload, and lipid peroxidation
Thom H, Carter PE, Cole GF, et al
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