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The studies had similar outcomes: DPP-4 inhibition and sulfonylurea both reduced HbA1c, DPP-4 inhibition had no weight gain, which on the contrary was seen with sulfonylurea, and there was a marked difference in hypoglycemia episodes
Interestingly, the 10 familial medullary thyroid carcinomas of the MEN 2 type, however, were all found to be negative for these receptors
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