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The strategies for when tirzepatide results plateau translate well to maintenance challenges, as many of the underlying principles are the same
gentle swirling is sufficient if mixing is required Minimise the number of times the vial is accessed, as repeated needle punctures increase contamination risk Label the vial clearly with the date and time of reconstitution, and with the sponsor-validated beyond-use date Follow all additional handling instructions specified in the IMP label or protocol These measures help to slow the degradation processes described above
Gentle Efficacy: The ability to achieve results without irritation means consistent, long-term use is more feasible, leading to better outcomes over time
2020;192(31):E875-E891
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