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In addition to carnosic acid, triptolide showed significant anticancer properties and amplified the in vitro and in vivo anticancer activity of various chemotherapeutic agents, including cisplatin (380382), paclitaxel (383), hydroxycamptothecin (384, 385), gemcitabine (386), and doxorubicin (387), in several cancer types, including bladder (EJ, UMUC3, and T24R2), breast (MDA-MB-231, BT549, and MCF7), lung (A549), and gastric (SC-M1) cancer cell lines
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We also acknowledge the use of the University of Wollongong Cryogenic Electron Microscopy Facility at Molecular Horizons
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