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For the composite endpoint of 1.0%-point HbA1c reduction with weight loss 3.0%, the cost of control was USD 525 lower with oral semaglutide 14 mg than with empagliflozin 25 mg
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24 Small molecules may offer advantages such as improved tissue permeability, longer half-lives, and lower production costs
To examine the effects of mutations on chaperone-like activity, OsDHAR WT, K8A, C20A, or K47A (0.2 mg/mL) was added to CAT (0.1 mg/mL) in the same reaction mixture and then heated at 60 C for 22 min
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