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Clinical trials have demonstrated significant weight loss in participants taking both medications, suggesting they can be effective weight loss tools when combined with diet and exercise
Carnitine supplements may help relieve constipation and correct carnitine deficiency in these populations
A practical, three-step approach adapted from current World Health Organization (56), American College of Sports Medicine (57), American Diabetes Association (58), and European Association for the Study of Obesity (59) guidelines is recommended: (1) introduce regular movement gradually, targeting 150 minutes of moderate-intensity or 75 minutes of vigorous aerobic activity per week (60)
Eating small, frequent meals with minimal fat and fiber slows stomach content further, reducing the contrast that triggers the nausea signal
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