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BiSpekDAb engineered by fusing anti-IL-23 domain antibody (VHH) and anti-TNF- domain antibody (VHH) to the 3rd domain of human serum albumin (3dHSA), using flexible linkers (GGGGS)
Transforming growth factor (TGF-) and insulin growth factor (IGF) are crucial in these processes, with GHK-Cu shown to decrease IGF-2-dependent TGF-1 secretion in dermal fibroblasts, potentially preventing hypertrophic scar formation
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It activates the Wnt/beta-catenin signaling pathway, which plays a central role in hair follicle development and cycling
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