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Contraindications Based on mechanism of action and conservative interpretation of potential risks, BPC-157 use is generally discouraged in individuals with active or recent cancer, pregnancy or breastfeeding, autoimmune conditions with active flares, children and adolescents (unknown effects on development), and known hypersensitivity to any peptide compounds
Future Research Directions and Emerging Applications Systemic Administration and Biodistribution Studies While most clinical applications of GHK-Cu involve topical administration, emerging research explores systemic delivery routes including subcutaneous injection, intravenous infusion, and oral administration for potential applications in systemic inflammation, tissue remodeling, and age-related decline
doi:10.3390/ijms23031851
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