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50 Consistent with these sex and compartment-dependent effects, our preliminary data showed that an 8-week, 30% CR regimen induced cortical bone loss in both sexes, whereas trabecular bone mass was enhanced in females
This is consistent with the previous findings that hypoxia-response genes were upregulated in the islets of diabetic, but not prediabetic, db/db mice in an inverse relationship with unfolded protein response gene expression 28,33
Role of Nrf2/HO-1 Signal axis in the Mechanisms for Oxidative Stress-Relevant Diseases
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