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Gene expression modulation influences thousands of genes related to growth, repair, and metabolic regulation

It carries a Boxed Warning the FDAs most serious safety alert due to a potential increased risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), based on findings from animal studies

Surgical procedures were approved by the Garvan Institute/St Vincents Hospital Animal Ethics Committee (Animal Research Authority 23_11) under the Australian Code of Practice for the Care and Use of Animals for Scientific Purposes