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Metabolic and Immune Support Beyond its antioxidant role, glutathione is necessary for healthy carbohydrate metabolism and is involved in metabolizing insulin and regulating blood glucose levels already in the normal range
In March 2024, the FDA approved a label expansion for Novo Nordisks Wegovy (semaglutide) to reduce the risk of cardiovascular death, heart attack and stroke in adults with cardiovascular disease and obesity or overweight
Phase 3 trials are much larger (thousands of participants), longer (often 2+ years), and are the stage required for regulatory approval
SURMOUNT-1 (Jastreboff et al., NEJM 2022) reported 22.5% body weight loss at 72 weeks at the 15 mg dose
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