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In animal models, glial cells such as astrocytes and NG2 oligodendrocyte precursor cells can be directly converted into functional neurons in vivo via ectopic expression of neurogenic transcription factors like NeuroD1 and Ascl1
It's not about one being definitively 'better' than the other
Duration of maintenance dosing The phase 2 trial ran for 48 weeks, and the weight loss curve had not fully plateaued by that point
We believe GLP-1 drugs will be one of the most impactful technologies in the US over the next five years (as we argued in our previous essay on GLP-1s)
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