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Chronic alcohol use creates baseline suppression of GHRH tone and hepatic IGF-1 synthesis, reducing peptide therapy outcomes by 3060% over three months compared to abstinent users
Conclusion: ASK1 inhibition suppresses profibrogenic release of mtDNA from dying hepatocytes in p38-dependent manner and protects from liver fibrosis
Psychiatry 26 , 13101320 (2021)
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