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This gradual titration helps the body adapt to the medication and reduces the likelihood of experiencing potential side effects, such as nausea, vomiting, or gastrointestinal discomfort

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The study, conducted 4,489 of US adults (including 332 currently taking a GLP-1 and 151 no longer on the medication) found that most individuals taking GLP-1s for weight loss do not expect to stay on them long-term

At week 26, the primary HbA1c endpoint was missing for 4.3%, 4.4% and 4.4% of patients randomized to placebo, RYBELSUS 7 mg and RYBELSUS 14 mg, respectively